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Transcription-induced formation of extrachromosomal DNA during yeast ageing
Extrachromosomal circular DNA (eccDNA) facilitates adaptive evolution by allowing rapid and extensive gene copy number variation and is implicated in the pathology of cancer and ageing. Here, we demonstrate that yeast aged under environmental copper accumulate high levels of eccDNA containing the co...
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| Veröffentlicht in: | PLoS Biol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6890164/ https://ncbi.nlm.nih.gov/pubmed/31794573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000471 |
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