Vav1 inhibits RANKL-induced osteoclast differentiation and bone resorption

Vav1 is a Rho/Rac guanine nucleotide exchange factor primarily expressed in hematopoietic cells. In this study, we investigated the potential role of Vav1 in osteoclast (OC) differentiation by comparing the ability of bone marrow mononuclear cells (BMMCs) obtained from Vav1-deficient (Vav1(−/−)) and...

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Vydáno v:BMB Rep
Hlavní autoři: Jang, Jin Sun, Kang, In Soon, Cha, Young-Nam, Lee, Zang Hee, Dinauer, Mary C, Kim, Young-June, Kim, Chaekyun
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Biochemistry and Molecular Biology 2019
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889896/
https://ncbi.nlm.nih.gov/pubmed/31072447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2019.52.11.013
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