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Aesculetin Inhibits Bone Resorption Through Down-Regulating Differentiation and Lysosomal Formation in Osteoclasts

OBJECTIVES: For the optimal resorption of mineralized bone extracellular matrix, osteoclasts require the generation of a resorption lacuna characterized by the presence of specific proteases and a low pH. Thus, bone resorption by osteoclasts highly rely on lysosomes, the organelles specialized in in...

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Detalhes bibliográficos
Publicado no:Curr Dev Nutr
Main Authors: Na, WooJin, Kang, Young-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7258109/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa045_075
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