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Vav1 inhibits RANKL-induced osteoclast differentiation and bone resorption

Vav1 is a Rho/Rac guanine nucleotide exchange factor primarily expressed in hematopoietic cells. In this study, we investigated the potential role of Vav1 in osteoclast (OC) differentiation by comparing the ability of bone marrow mononuclear cells (BMMCs) obtained from Vav1-deficient (Vav1(−/−)) and...

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Detalhes bibliográficos
Publicado no:BMB Rep
Main Authors: Jang, Jin Sun, Kang, In Soon, Cha, Young-Nam, Lee, Zang Hee, Dinauer, Mary C, Kim, Young-June, Kim, Chaekyun
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889896/
https://ncbi.nlm.nih.gov/pubmed/31072447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2019.52.11.013
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