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NADPH oxidase gp91(phox) contributes to RANKL-induced osteoclast differentiation by upregulating NFATc1

Bone-marrow derived monocyte-macrophages (BMMs) differentiate into osteoclasts by M-CSF along subsequent RANKL stimulation possibly in collaboration with many other unknown cytokines released by pre- or mature osteoblasts. The differentiation process requires receptor activator of nuclear factor kap...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Kang, In Soon, Kim, Chaekyun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126560/
https://ncbi.nlm.nih.gov/pubmed/27897222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38014
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