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Epoxyeicosatrienoic acid (EET)-stimulated angiogenesis is mediated by epoxy hydroxyeicosatrienoic acids (EHETs) formed from COX-2

Epoxyeicosatrienoic acids (EETs) are formed from the metabolism of arachidonic acid by cytochrome P450s. EETs promote angiogenesis linked to tumor growth in various cancer models that is attenuated in vivo by cyclooxygenase 2 (COX-2) inhibitors. This study further defines a role for COX-2 in mediati...

詳細記述

保存先:
書誌詳細
出版年:J Lipid Res
主要な著者: Rand, Amy A., Rajamani, Anita, Kodani, Sean D., Harris, Todd R., Schlatt, Lukas, Barnych, Bodgan, Passerini, Anthony G., Hammock, Bruce D.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Biochemistry and Molecular Biology 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889709/
https://ncbi.nlm.nih.gov/pubmed/31641036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M094219
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