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Inhibition of Carcinoma Cell Motility by Epoxyeicosatrienoic Acid (EET) Antagonists

Cytochrome P450 (CYP) epoxygenases, CYP2C8, 2C9 and 2J2 mRNAs and proteins, were expressed in prostate carcinoma (PC-3, DU-145 and LNCaP) cells. 11,12-Epoxyeicosatrienoic acid (11,12-EET) was the major arachidonic acid metabolite in these cells. Blocking the EET synthesis by a selective CYP epoxygen...

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Bibliographische Detailangaben
Hauptverfasser: Nithipatikom, Kasem, Brody, Daniel M., Tang, Alan T., Manthati, Vijaya L., Falck, John R., Williams, Carol L., Campbell, William B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398840/
https://ncbi.nlm.nih.gov/pubmed/20804500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2010.01713.x
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