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Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs)

Early on, intriguing biological activities were found associated with the EETs using in vitro systems. Although the EETs other than the 5,6-isomer, are quite stable chemically, they are quickly degraded enzymatically with the sEH accounting in many cases for much of the metabolism. This rapid degrad...

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Detalhes bibliográficos
Main Authors: Inceoglu, Bora, Schmelzer, Kara R., Morisseau, Christophe, Jinks, Steve L., Hammock, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904338/
https://ncbi.nlm.nih.gov/pubmed/17164131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2006.05.004
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