Leukemic stem cell signatures identify novel therapeutics targeting acute myeloid leukemia

Therapy for acute myeloid leukemia (AML) involves intense cytotoxic treatment and yet approximately 70% of AML are refractory to initial therapy or eventually relapse. This is at least partially driven by the chemo-resistant nature of the leukemic stem cells (LSCs) that sustain the disease, and ther...

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Udgivet i:Blood Cancer J
Main Authors: Laverdière, Isabelle, Boileau, Meaghan, Neumann, Andrea L., Frison, Héloïse, Mitchell, Amanda, Ng, Stanley W. K., Wang, Jean C. Y., Minden, Mark D., Eppert, Kolja
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889502/
https://ncbi.nlm.nih.gov/pubmed/29921955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-018-0087-2
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