A 6-gene leukemic stem cell score identifies high risk pediatric acute myeloid leukemia

Recently, mRNA-expression signature enriched in LSCs was used to create a 17-gene leukemic stem cell (LSC17) score predictive of prognosis in adult AML. By fitting a Cox-LASSO regression model to the clinical outcome and gene-expression levels of LSC enriched genes in 163 pediatric participants of t...

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Bibliografiset tiedot
Julkaisussa:Leukemia
Päätekijät: Elsayed, Abdelrahman H., Rafiee, Roya, Cao, Xueyuan, Raimondi, Susana, Downing, James R., Ribeiro, Raul, Fan, Yiping, Gruber, Tanja A., Baker, Sharyn, Klco, Jeffery, Rubnitz, Jeffrey E., Pounds, Stanley, Lamba, Jatinder K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7135934/
https://ncbi.nlm.nih.gov/pubmed/31645648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0604-8
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