Integrated epigenetic and genetic analysis identifies markers of prognostic significance in pediatric acute myeloid leukemia

Acute myeloid leukemia (AML) may be an epigenetically-driven malignancy because it harbors fewer genomic mutations than other cancers. In recent studies of AML in adults, DNA methylation patterns associate with clinical risk groups and prognosis. However, thorough evaluations of methylation in pedia...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lamba, Jatinder K., Cao, Xueyuan, Raimondi, Susana C., Rafiee, Roya, Downing, James R., Lei, Shi, Gruber, Tanja, Ribeiro, Raul C., Rubnitz, Jeffrey E., Pounds, Stanley B.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003565/
https://ncbi.nlm.nih.gov/pubmed/29928480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25475
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