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LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer

LRIG1 has been reported to be a tumor suppressor in gastrointestinal tract and epidermis. However, little is known about the expression, regulation and biological functions of LRIG1 in prostate cancer (PCa). We find that LRIG1 is overexpressed in PCa, but its expression correlates with better patien...

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發表在:Nat Commun
Main Authors: Li, Qiuhui, Liu, Bigang, Chao, Hsueh-Ping, Ji, Yibing, Lu, Yue, Mehmood, Rashid, Jeter, Collene, Chen, Taiping, Moore, John R., Li, Wenqian, Liu, Can, Rycaj, Kiera, Tracz, Amanda, Kirk, Jason, Calhoun-Davis, Tammy, Xiong, Jie, Deng, Qu, Huang, Jiaoti, Foster, Barbara A., Gokhale, Abhiram, Chen, Xin, Tang, Dean G.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889295/
https://ncbi.nlm.nih.gov/pubmed/31792211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13532-4
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