Defining a population of stem-like human prostate cancer cells that can generate and propagate castration-resistant prostate cancer (CRPC)

PURPOSE: We have shown that the phenotypically undifferentiated (PSA(−/lo)) prostate cancer (PCa) cell population harbors long-term self-renewing cancer stem cells (CSCs) that resist castration and a subset of the cells within PSA(−/lo) population bearing the ALDH(hi)CD44(+)α2β1(+) phenotype (Triple...

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Publié dans:Clin Cancer Res
Auteurs principaux: Chen, Xin, Li, Qiuhui, Liu, Xin, Liu, Can, Liu, Ruifang, Rycaj, Kiera, Zhang, Dingxiao, Liu, Bigang, Jeter, Collene, Calhoun-Davis, Tammy, Lin, Kevin, Lu, Yue, Chao, Hsueh-Ping, Shen, Jianjun, Tang, Dean G.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010458/
https://ncbi.nlm.nih.gov/pubmed/27060154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2956
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