Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses

Expression of androgen receptor (AR) in prostate cancer (PCa) is heterogeneous but the functional significance of AR heterogeneity remains unclear. Screening ~200 castration-resistant PCa (CRPC) cores and whole-mount sections (from 89 patients) reveals 3 AR expression patterns: nuclear (nuc-AR), mix...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Li, Qiuhui, Deng, Qu, Chao, Hsueh-Ping, Liu, Xin, Lu, Yue, Lin, Kevin, Liu, Bigang, Tang, Gregory W., Zhang, Dingxiao, Tracz, Amanda, Jeter, Collene, Rycaj, Kiera, Calhoun-Davis, Tammy, Huang, Jiaoti, Rubin, Mark A., Beltran, Himisha, Shen, Jianjun, Chatta, Gurkamal, Puzanov, Igor, Mohler, James L., Wang, Jianmin, Zhao, Ruizhe, Kirk, Jason, Chen, Xin, Tang, Dean G.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127155/
https://ncbi.nlm.nih.gov/pubmed/30190514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06067-7
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki