miR-199a-3p targets stemness-related and mitogenic signaling pathways to suppress the expansion and tumorigenic capabilities of prostate cancer stem cells

Human cancers exhibit significant cellular heterogeneity featuring tumorigenic cancer stem cells (CSCs) in addition to more differentiated progeny with limited tumor-initiating capabilities. Recent studies suggest that microRNAs (miRNAs) regulate CSCs and tumor development. A previous library screen...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Ruifang, Liu, Can, Zhang, Dingxiao, Liu, Bigang, Chen, Xin, Rycaj, Kiera, Jeter, Collene, Calhoun-Davis, Tammy, Li, Yandong, Yang, Tao, Wang, Junchen, Tang, Dean G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302940/
https://ncbi.nlm.nih.gov/pubmed/27447749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10652
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