miR-199a-3p targets stemness-related and mitogenic signaling pathways to suppress the expansion and tumorigenic capabilities of prostate cancer stem cells

Human cancers exhibit significant cellular heterogeneity featuring tumorigenic cancer stem cells (CSCs) in addition to more differentiated progeny with limited tumor-initiating capabilities. Recent studies suggest that microRNAs (miRNAs) regulate CSCs and tumor development. A previous library screen...

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Vydáno v:Oncotarget
Hlavní autoři: Liu, Ruifang, Liu, Can, Zhang, Dingxiao, Liu, Bigang, Chen, Xin, Rycaj, Kiera, Jeter, Collene, Calhoun-Davis, Tammy, Li, Yandong, Yang, Tao, Wang, Junchen, Tang, Dean G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302940/
https://ncbi.nlm.nih.gov/pubmed/27447749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10652
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