miR-199a-3p targets stemness-related and mitogenic signaling pathways to suppress the expansion and tumorigenic capabilities of prostate cancer stem cells

Human cancers exhibit significant cellular heterogeneity featuring tumorigenic cancer stem cells (CSCs) in addition to more differentiated progeny with limited tumor-initiating capabilities. Recent studies suggest that microRNAs (miRNAs) regulate CSCs and tumor development. A previous library screen...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Liu, Ruifang, Liu, Can, Zhang, Dingxiao, Liu, Bigang, Chen, Xin, Rycaj, Kiera, Jeter, Collene, Calhoun-Davis, Tammy, Li, Yandong, Yang, Tao, Wang, Junchen, Tang, Dean G.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302940/
https://ncbi.nlm.nih.gov/pubmed/27447749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10652
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