MicroRNA-141 suppresses prostate cancer stem cells and metastasis by targeting a cohort of pro-metastasis genes

MicroRNAs play important roles in regulating tumour development, progression and metastasis. Here we show that one of the miR-200 family members, miR-141, is under-expressed in several prostate cancer (PCa) stem/progenitor cell populations in both xenograft and primary patient tumours. Enforced expr...

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Vydáno v:Nat Commun
Hlavní autoři: Liu, Can, Liu, Ruifang, Zhang, Dingxiao, Deng, Qu, Liu, Bigang, Chao, Hsueh-Ping, Rycaj, Kiera, Takata, Yoko, Lin, Kevin, Lu, Yue, Zhong, Yi, Krolewski, John, Shen, Jianjun, Tang, Dean G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264244/
https://ncbi.nlm.nih.gov/pubmed/28112170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14270
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