LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer

LRIG1 has been reported to be a tumor suppressor in gastrointestinal tract and epidermis. However, little is known about the expression, regulation and biological functions of LRIG1 in prostate cancer (PCa). We find that LRIG1 is overexpressed in PCa, but its expression correlates with better patien...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Li, Qiuhui, Liu, Bigang, Chao, Hsueh-Ping, Ji, Yibing, Lu, Yue, Mehmood, Rashid, Jeter, Collene, Chen, Taiping, Moore, John R., Li, Wenqian, Liu, Can, Rycaj, Kiera, Tracz, Amanda, Kirk, Jason, Calhoun-Davis, Tammy, Xiong, Jie, Deng, Qu, Huang, Jiaoti, Foster, Barbara A., Gokhale, Abhiram, Chen, Xin, Tang, Dean G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889295/
https://ncbi.nlm.nih.gov/pubmed/31792211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13532-4
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