The Hypervariable Region of K-Ras4B Governs Molecular Recognition and Function

The flexible C-terminal hypervariable region distinguishes K-Ras4B, an important proto-oncogenic GTPase, from other Ras GTPases. This unique lysine-rich portion of the protein harbors sites for post-translational modification, including cysteine prenylation, carboxymethylation, phosphorylation, and...

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Gardado en:
Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Abdelkarim, Hazem, Banerjee, Avik, Grudzien, Patrick, Leschinsky, Nicholas, Abushaer, Mahmoud, Gaponenko, Vadim
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888304/
https://ncbi.nlm.nih.gov/pubmed/31739603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20225718
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