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The hypervariable region of K-Ras4B is responsible for its specific interactions with Calmodulin
K-Ras4B belongs to the family of p21 Ras GTPases, which play an important role in cell proliferation, survival and motility. The p21 Ras proteins such as K-Ras4B, K-Ras4A, H-Ras, and N-Ras, share 85% sequence homology and activate very similar signaling pathways. Only the C-terminal hypervariable re...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729490/ https://ncbi.nlm.nih.gov/pubmed/19583261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900769j |
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