AAV-mediated gene therapy targeting TRPV4 mechanotransduction for inhibition of pulmonary vascular leakage

Enhanced vascular permeability in the lungs can lead to pulmonary edema, impaired gas exchange, and ultimately respiratory failure. While oxygen delivery, mechanical ventilation, and pressure-reducing medications help alleviate these symptoms, they do not treat the underlying disease. Mechanical act...

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Detalhes bibliográficos
Publicado no:APL Bioeng
Main Authors: Li, Juan, Wen, Amy M., Potla, Ratnakar, Benshirim, Ezekiel, Seebarran, Ariel, Benz, Maximilian A., Henry, Olivier Y. F., Matthews, Benjamin D., Prantil-Baun, Rachelle, Gilpin, Sarah E., Levy, Oren, Ingber, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: AIP Publishing LLC 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887658/
https://ncbi.nlm.nih.gov/pubmed/31803860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5122967
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