AAV-mediated gene therapy targeting TRPV4 mechanotransduction for inhibition of pulmonary vascular leakage

Enhanced vascular permeability in the lungs can lead to pulmonary edema, impaired gas exchange, and ultimately respiratory failure. While oxygen delivery, mechanical ventilation, and pressure-reducing medications help alleviate these symptoms, they do not treat the underlying disease. Mechanical act...

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Dettagli Bibliografici
Pubblicato in:APL Bioeng
Autori principali: Li, Juan, Wen, Amy M., Potla, Ratnakar, Benshirim, Ezekiel, Seebarran, Ariel, Benz, Maximilian A., Henry, Olivier Y. F., Matthews, Benjamin D., Prantil-Baun, Rachelle, Gilpin, Sarah E., Levy, Oren, Ingber, Donald E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: AIP Publishing LLC 2019
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887658/
https://ncbi.nlm.nih.gov/pubmed/31803860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5122967
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