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Pd‐Catalyzed Allylation of Imines to Access α‐CF(3)‐Substituted α‐Amino Acid Derivatives

We herein report a high yielding protocol for the direct α‐allylation of easily accessible trifluoropyruvate‐derived imines using Pd‐catalysis. The reaction gives access to a variety of different α‐allylated‐α‐CF(3)‐amino acids in a straightforward manner, starting from commercially available triflu...

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Detalhes bibliográficos
Publicado no:European J Org Chem
Main Authors: Winter, Michael, Kim, Hyunwoo, Waser, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887540/
https://ncbi.nlm.nih.gov/pubmed/31798337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201901272
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