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Pd-catalyzed asymmetric allylic alkylations via C–H activation of N-allyl imines with glycinates

Herein is reported the first example of palladium-catalyzed asymmetric allylic alkylation (AAA) reactions involving 2-aza-π-allyl palladium intermediates. The 2-aza-π-allyl complex was generated via a novel mode of activation of N-allyl imines. Pd-catalyzed C(sp(3))–H activation of N-allyl imines an...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Trost, Barry M., Li, Xiaoxun
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643980/
https://ncbi.nlm.nih.gov/pubmed/29147506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc02899g
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