טוען...
Interplay between affinity and valency in effector cell degranulation: a model system with polcalcin allergens and human patient-derived IgE antibodies
An allergic reaction is rapidly generated when allergens bind and crosslink immunoglobulin E bound to its receptor FcεRI on effector cells, resulting in cell degranulation and release of pro-inflammatory mediators. The extent of effector cell activation is linked to allergen affinity, oligomeric sta...
שמור ב:
| הוצא לאור ב: | J Immunol |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6887533/ https://ncbi.nlm.nih.gov/pubmed/31462504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900509 |
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