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A Heterobivalent Ligand Inhibits Mast Cell Degranulation via Selective Inhibition of Allergen-IgE Interactions In Vivo

Current treatments for allergies include epinephrine and anti-histamines which treat the symptoms after an allergic response has taken place, steroids that result in local and systemic immune suppression and IgE-depleting therapies which can only be used for a narrow range of clinical IgE titers. Th...

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Hlavní autoři: Handlogten, Michael W., Serezani, Ana P., Sinn, Anthony L., Pollok, Karen E., Kaplan, Mark H., Bilgicer, Basar
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951166/
https://ncbi.nlm.nih.gov/pubmed/24489096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301371
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