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Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death
As pathogenic Parkin mutations result in the defective clearance of damaged mitochondria, Parkin-dependent mitophagy is thought to be protective against the dopaminergic neurodegeneration observed in Parkinson’s disease. Recent studies, however, have demonstrated that Parkin can promote cell death i...
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| Vydáno v: | Cell Death Dis |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6885512/ https://ncbi.nlm.nih.gov/pubmed/31787745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2132-x |
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