BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62

Molecular chaperones are critical to maintaining intracellular proteostasis and have been shown to have a protective role against alpha-synuclein-mediated toxicity. Co-chaperone proteins regulate the activity of molecular chaperones and connect the chaperone network to protein degradation and cell d...

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Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Friesen, Erik L., Zhang, Yu Tong, Earnshaw, Rebecca, De Snoo, Mitch L., O’Hara, Darren M., Agapova, Victoria, Chau, Hien, Ngana, Sophie, Chen, Kevin S., Kalia, Lorraine V., Kalia, Suneil K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417480/
https://ncbi.nlm.nih.gov/pubmed/32850835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00716
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