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Ubiquitinylation of α-Synuclein by Carboxyl Terminus Hsp70-Interacting Protein (CHIP) Is Regulated by Bcl-2-Associated Athanogene 5 (BAG5)

Parkinson's disease (PD) is a common neurodegenerative condition in which abnormalities in protein homeostasis, or proteostasis, may lead to accumulation of the protein α-synuclein (α-syn). Mutations within or multiplications of the gene encoding α-syn are known to cause genetic forms of PD and...

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Detalhes bibliográficos
Main Authors: Kalia, Lorraine V., Kalia, Suneil K., Chau, Hien, Lozano, Andres M., Hyman, Bradley T., McLean, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040167/
https://ncbi.nlm.nih.gov/pubmed/21358815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014695
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