Lipid order and charge protect killer T cells from accidental death

Killer T cells (cytotoxic T lymphocytes, CTLs) maintain immune homoeostasis by eliminating virus-infected and cancerous cells. CTLs achieve this by forming an immunological synapse with their targets and secreting a pore-forming protein (perforin) and pro-apoptotic serine proteases (granzymes) into...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rudd-Schmidt, Jesse A., Hodel, Adrian W., Noori, Tahereh, Lopez, Jamie A., Cho, Hyun-Jung, Verschoor, Sandra, Ciccone, Annette, Trapani, Joseph A., Hoogenboom, Bart W., Voskoboinik, Ilia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881447/
https://ncbi.nlm.nih.gov/pubmed/31776337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13385-x
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