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The balance between NRF2/GSH antioxidant mediated pathway and DNA repair modulates cisplatin resistance in lung cancer cells

Lung cancer patients face a dismal prognosis mainly due to the low efficacy of current available treatments. Cisplatin is the first-line chemotherapy treatment for those patients, however, resistance to this drug is a common and yet not fully understood phenomenon. Aiming to shed new light into this...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Silva, Matheus Molina, Rocha, Clarissa Ribeiro Reily, Kinker, Gabriela Sarti, Pelegrini, Alessandra Luiza, Menck, Carlos Frederico Martins
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881285/
https://ncbi.nlm.nih.gov/pubmed/31776385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54065-6
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