DNA repair pathways and cisplatin resistance: an intimate relationship

The main goal of chemotherapeutic drugs is to induce massive cell death in tumors. Cisplatin is an antitumor drug widely used to treat several types of cancer. Despite its remarkable efficiency, most tumors show intrinsic or acquired drug resistance. The primary biological target of cisplatin is gen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clinics (Sao Paulo)
Hauptverfasser: Rocha, Clarissa Ribeiro Reily, Silva, Matheus Molina, Quinet, Annabel, Cabral-Neto, Januario Bispo, Menck, Carlos Frederico Martins
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2018
Schlagworte:
Review Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113849/
https://ncbi.nlm.nih.gov/pubmed/30208165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6061/clinics/2018/e478s
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