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NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells

Cancer is a leading cause of death worldwide, and while great advances have been made particularly in chemotherapy, many types of cancer still present a dismal prognosis. In the case of glioma, temozolomide (TMZ) is the main option for treatment, but it has limited success due to drug resistance. Wh...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Rocha, Clarissa Ribeiro Reily, Kajitani, Gustavo Satoru, Quinet, Annabel, Fortunato, Rodrigo Soares, Menck, Carlos Frederico Martins
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217002/
https://ncbi.nlm.nih.gov/pubmed/27344172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10129
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