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Apnea Associated with Brainstem Seizures in Cacna1a(S218L) Mice Is Caused by Medullary Spreading Depolarization

Seizure-related apnea is common and can be lethal. Its mechanisms however remain unclear and preventive strategies are lacking. We postulate that brainstem spreading depolarization (SD), previously associated with lethal seizures in animal models, initiates apnea upon invasion of brainstem respirato...

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Библиографические подробности
Опубликовано в: :J Neurosci
Главные авторы: Jansen, Nico A., Schenke, Maarten, Voskuyl, Rob. A., Thijs, Roland D., van den Maagdenberg, Arn M.J.M., Tolner, Else A.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880468/
https://ncbi.nlm.nih.gov/pubmed/31628185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1713-19.2019
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