Impaired θ-γ Coupling Indicates Inhibitory Dysfunction and Seizure Risk in a Dravet Syndrome Mouse Model

Dravet syndrome (DS) is an epileptic encephalopathy that still lacks biomarkers for epileptogenesis and its treatment. Dysfunction of Na(V)1.1 sodium channels, which are chiefly expressed in inhibitory interneurons, explains the epileptic phenotype. Understanding the network effects of these cellula...

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發表在:J Neurosci
Main Authors: Jansen, Nico A., Perez, Carlos, Schenke, Maarten, van Beurden, Anouk W., Dehghani, Anisa, Voskuyl, Rob A., Thijs, Roland D., Ullah, Ghanim, van den Maagdenberg, Arn M.J.M., Tolner, Else A.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2021
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821857/
https://ncbi.nlm.nih.gov/pubmed/33234612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2132-20.2020
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