Apnea Associated with Brainstem Seizures in Cacna1a(S218L) Mice Is Caused by Medullary Spreading Depolarization

Seizure-related apnea is common and can be lethal. Its mechanisms however remain unclear and preventive strategies are lacking. We postulate that brainstem spreading depolarization (SD), previously associated with lethal seizures in animal models, initiates apnea upon invasion of brainstem respirato...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Jansen, Nico A., Schenke, Maarten, Voskuyl, Rob. A., Thijs, Roland D., van den Maagdenberg, Arn M.J.M., Tolner, Else A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880468/
https://ncbi.nlm.nih.gov/pubmed/31628185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1713-19.2019
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