First FHM3 mouse model shows spontaneous cortical spreading depolarizations

Here we show, for the first time, spontaneous cortical spreading depolarization (CSD) events – the electrophysiological correlate of the migraine aura – in animals by using the first generated familial hemiplegic migraine type 3 (FHM3) transgenic mouse model. The mutant mice express L263V‐mutated α1...

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Bibliographic Details
Published in:	Ann Clin Transl Neurol
Main Authors:	Jansen, Nico A., Dehghani, Anisa, Linssen, Margot M. L., Breukel, Cor, Tolner, Else A., van den Maagdenberg, Arn M. J. M.
Format:	Artigo
Language:	Inglês
Published:	John Wiley and Sons Inc. 2019
Subjects:	Brief Communications
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6952313/ https://ncbi.nlm.nih.gov/pubmed/31880072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.50971
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First FHM3 mouse model shows spontaneous cortical spreading depolarizations

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