First FHM3 mouse model shows spontaneous cortical spreading depolarizations

Here we show, for the first time, spontaneous cortical spreading depolarization (CSD) events – the electrophysiological correlate of the migraine aura – in animals by using the first generated familial hemiplegic migraine type 3 (FHM3) transgenic mouse model. The mutant mice express L263V‐mutated α1...

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Detalles Bibliográficos
Publicado en:Ann Clin Transl Neurol
Autores principales: Jansen, Nico A., Dehghani, Anisa, Linssen, Margot M. L., Breukel, Cor, Tolner, Else A., van den Maagdenberg, Arn M. J. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
Materias:
Brief Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952313/
https://ncbi.nlm.nih.gov/pubmed/31880072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.50971
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