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Using Chemical Inhibitors to Probe AAA protein conformational dynamics and cellular functions

The AAA proteins are a family of enzymes that play key roles in diverse dynamic cellular processes, ranging from proteostasis to directional intracellular transport. Dysregulation of AAA proteins has been linked to several diseases, including cancer, suggesting a possible therapeutic role for inhibi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Curr Opin Chem Biol
Päätekijät: Steinman, Jonathan B, Kapoor, Tarun M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880239/
https://ncbi.nlm.nih.gov/pubmed/30913482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2019.02.019
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