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Using Chemical Inhibitors to Probe AAA protein conformational dynamics and cellular functions
The AAA proteins are a family of enzymes that play key roles in diverse dynamic cellular processes, ranging from proteostasis to directional intracellular transport. Dysregulation of AAA proteins has been linked to several diseases, including cancer, suggesting a possible therapeutic role for inhibi...
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| Veröffentlicht in: | Curr Opin Chem Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6880239/ https://ncbi.nlm.nih.gov/pubmed/30913482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2019.02.019 |
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