Neuroprotective effects of protocatechuic aldehyde through PLK2/p-GSK3β/Nrf2 signaling pathway in both in vivo and in vitro models of Parkinson's disease

Mitochondrial dysfunction and oxidative damage are closely related to the pathogenesis of Parkinson's disease (PD). The pharmacological mechanism of protocatechuic aldehyde (PCA) for PD treatment have retained unclear. The purposes of the present study were to clarify the neuroprotective effect...

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Guo, Chao, Zhu, Junrong, Wang, Jingwen, Duan, Jialin, Ma, Shanbo, Yin, Ying, Quan, Wei, Zhang, Wei, Guan, Yue, Ding, Yi, Wen, Aidong, Zhang, Yingdong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874433/
https://ncbi.nlm.nih.gov/pubmed/31697645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102394
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