Neuroprotective effects of protocatechuic aldehyde through PLK2/p-GSK3β/Nrf2 signaling pathway in both in vivo and in vitro models of Parkinson's disease

Mitochondrial dysfunction and oxidative damage are closely related to the pathogenesis of Parkinson's disease (PD). The pharmacological mechanism of protocatechuic aldehyde (PCA) for PD treatment have retained unclear. The purposes of the present study were to clarify the neuroprotective effect...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Guo, Chao, Zhu, Junrong, Wang, Jingwen, Duan, Jialin, Ma, Shanbo, Yin, Ying, Quan, Wei, Zhang, Wei, Guan, Yue, Ding, Yi, Wen, Aidong, Zhang, Yingdong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874433/
https://ncbi.nlm.nih.gov/pubmed/31697645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102394
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