Apigenin-7-O-β-D-(-6”-p-coumaroyl)-glucopyranoside treatment elicits a neuroprotective effect through GSK-3β phosphorylation-mediated Nrf2 activation

The current study was designed to seek the role of the glycogen synthase kinase-3β (GSK-β)-regulated NF-E2-related factor 2 (Nrf2) pathway in the antioxidant effect induced by Apigenin-7-O-β-D-(-6”-p-coumaroyl)-glucopyranoside (APG). Rat primary cultured cortical neurons were challenged by oxygen an...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Wang, Jingwen, Wang, Shiquan, Sun, Sisi, Lu, Yunyang, Gao, Kai, Guo, Chao, Li, Ruili, Li, Weiwei, Zhao, Xian, Tang, Haifeng, Wen, Aidong, Cai, Min, Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762462/
https://ncbi.nlm.nih.gov/pubmed/33263567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.104050
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