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Expression and regulation of telomerase in human T cell differentiation, activation, aging and diseases

Telomeres are essential for chromosomal integrity. Telomere shortening during cell division restricts cellular proliferative capacity and leads to cellular senescence when critically shortened telomere lengths are reached. Similar to hematopoietic stem cells, T cells can upregulate telomerase activi...

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Dades bibliogràfiques
Publicat a:Cell Immunol
Autors principals: Patrick, Michael, Weng, Nan-ping
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873926/
https://ncbi.nlm.nih.gov/pubmed/31558266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2019.103989
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