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Expression and regulation of telomerase in human T cell differentiation, activation, aging and diseases

Telomeres are essential for chromosomal integrity. Telomere shortening during cell division restricts cellular proliferative capacity and leads to cellular senescence when critically shortened telomere lengths are reached. Similar to hematopoietic stem cells, T cells can upregulate telomerase activi...

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Podrobná bibliografie
Vydáno v:Cell Immunol
Hlavní autoři: Patrick, Michael, Weng, Nan-ping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873926/
https://ncbi.nlm.nih.gov/pubmed/31558266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2019.103989
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