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Molecular regulation of telomerase activity in aging

The process of aging is mitigated by the maintenance and repair of chromosome ends (telomeres), resulting in extended lifespan. This review examines the molecular mechanisms underlying the actions and regulation of the enzyme telomerase reverse transcriptase (TERT), which functions as the primary me...

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Publicat a:Protein Cell
Autors principals: Nicholls, Craig, Li, He, Wang, Jian-Qiu, Liu, Jun-Ping
Format: Artigo
Idioma:Inglês
Publicat: Higher Education Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875265/
https://ncbi.nlm.nih.gov/pubmed/21976062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1093-3
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