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Expression and regulation of telomerase in human T cell differentiation, activation, aging and diseases

Telomeres are essential for chromosomal integrity. Telomere shortening during cell division restricts cellular proliferative capacity and leads to cellular senescence when critically shortened telomere lengths are reached. Similar to hematopoietic stem cells, T cells can upregulate telomerase activi...

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Detalhes bibliográficos
Publicado no:Cell Immunol
Main Authors: Patrick, Michael, Weng, Nan-ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873926/
https://ncbi.nlm.nih.gov/pubmed/31558266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2019.103989
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