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Distinct functions of AKT isoforms in breast cancer: a comprehensive review

BACKGROUND: AKT, also known as protein kinase B, is a key element of the PI3K/AKT signaling pathway. Moreover, AKT regulates the hallmarks of cancer, e.g. tumor growth, survival and invasiveness of tumor cells. After AKT was discovered in the early 1990s, further studies revealed that there are thre...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Hinz, Nico, Jücker, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873690/
https://ncbi.nlm.nih.gov/pubmed/31752925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0450-3
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