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Distinct functions of AKT isoforms in breast cancer: a comprehensive review

BACKGROUND: AKT, also known as protein kinase B, is a key element of the PI3K/AKT signaling pathway. Moreover, AKT regulates the hallmarks of cancer, e.g. tumor growth, survival and invasiveness of tumor cells. After AKT was discovered in the early 1990s, further studies revealed that there are thre...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Commun Signal
Asıl Yazarlar: Hinz, Nico, Jücker, Manfred
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873690/
https://ncbi.nlm.nih.gov/pubmed/31752925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0450-3
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