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Akt isoform specific effects in ovarian cancer progression

Ovarian cancer remains a significant therapeutic problem and novel, effective therapies are needed. Akt is a serine-threonine kinase that is overexpressed in numerous cancers, including ovarian. Mammalian cells express three Akt isoforms which are encoded by distinct genes. Although there are severa...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Linnerth-Petrik, Nicolle M., Santry, Lisa A., Moorehead, Roger, Jücker, Manfred, Wootton, Sarah K., Petrik, Jim
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342704/
https://ncbi.nlm.nih.gov/pubmed/27533079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11204
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