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Distinct functions of AKT isoforms in breast cancer: a comprehensive review

BACKGROUND: AKT, also known as protein kinase B, is a key element of the PI3K/AKT signaling pathway. Moreover, AKT regulates the hallmarks of cancer, e.g. tumor growth, survival and invasiveness of tumor cells. After AKT was discovered in the early 1990s, further studies revealed that there are thre...

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Bibliografski detalji
Izdano u:Cell Commun Signal
Glavni autori: Hinz, Nico, Jücker, Manfred
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873690/
https://ncbi.nlm.nih.gov/pubmed/31752925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0450-3
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